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‘IT MAKES A BIG DIFFERENCE’: Dim light is less of a problem now for Steven Howarth, 18, “a small change” that matters a lot to him. Researchers want to try the method in children next. BBCLeber's Congenital Amauros, a rare form of blindness that has not had any cure, is a disease that affects 3,000 people a year and 130,000 worldwide.  Recently there has been new hope for restoring site in patients suffering from the disease.  Researchers found that if they could begin gene therapy treatment before signal pathways begin to be unused in the brain, sight can be  markedly improved.  Gene therapy in voles injecting healthy replacement genes that can take over for defective ones in a patients genome.  The study is a landmark for vision loss.  One patient was able to read an eye chart while another one was able to run an obstacle course.  The hope is that with further research, patients suffering from other forms of eye disorders such as macular degeneration and pigmentosa will also have hope.

From the article:
Two weeks after the injections, all three patients reported improved vision in the injected eyes, Maguire said. By gauging pupillary response to light -- researchers' only objective measure of vision -- they found that light sensitivity had improved about threefold. The treatment also reduced nystagmus, an uncontrollable roaming of the eye common in blind people.

Read The Full Article (latimes.com)


Link to this page: Gene Therapy Helps Several Blind Patients See Better
Originally Published: 04/28/2008 by Thomas H. Maugh, II at The Los Angeles Times


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